Human Health

Sep. 1, 2019

Michael J. Petris

The micronutrient copper (Cu) is essential for several key enzymatic processes involved in energy generation, protection against reactive oxygen species, formation of blood vessels, immune function, and healthy functioning of the central nervous system. This nutrient is able to exist in two oxidation states Cu1+ and Cu2+, and participate in the generation of reactive oxygen species. A delicate balance of copper homeostasis must be maintained to provide sufficient levels of this nutrient, while preventing toxic build up. Copper and Cancer Recent evidence suggests that copper plays a key role in tumor growth because this metal…

Sep. 1, 2019

Brian Mooney

I am particularly interested in protocol and technology development for proteomics and mass spectrometry. We use mass spectrometry for protein identification, protein/peptide quantitation, and mapping sites of post-translational modifications and protein-protein interactions. Metastable Crystallins: Structure and stabilization (NEI-NIH award R01EY023219) Cataract and a host of other diseases result from abnormal interaction of proteins in the cells. The goals of this research are to understand lens protein aggregation in cataract formation and to develop and test lens protein alpha-crystallin-derived peptide as active mini-chaperones capable of suppressing protein aggregation. Understanding the structural changes in mutant proteins associated…

April 3, 2019

Kiruba Krishnaswamy

Krishnaswamy is an Associate Professor of Sustainable Food Systems Engineering at the University of Missouri, Columbia. She has a joint appointment in the Department of Chemical and Biomedical Engineering and the Division of Food, Nutrition, and Exercise Sciences. Her research program Food Engineering and Sustainable Technologies integrates convergence sciences with engineering principles to address the interconnected challenges of food and nutrition security. She uses a circular food systems approach to support the UN Sustainable Development Goals (SDGs). Krishnaswamy obtained her B.Tech. in Food Process Engineering from Tamil Nadu Agricultural University, India. She obtained the Canadian Commonwealth Scholarship for…

Feb. 19, 2019

Bill Folk

Educational background Courses taught…

Nov. 5, 2018

Amanda L. Patterson

Educational background Courses taught…

Dec. 14, 2017

Sonja A. Wilhelm Stanis

Educational background Courses taught…

Nov. 9, 2017

Jared E. Decker

IDENTIFYING LOCI RESPONDING TO SELECTIONIn 2012 Decker published a method, now called Generation-Proxy Selection Mapping, to identify loci responding to current selection. In this analysis, birth date (as a surrogate to generation number) is fit as the dependent variable in a mixed model equation. Variants that have changed in frequency rapidly due to selection are strongly associated with birth date, thus the method identifies regions under selection. The mixed model equations correct for demography, relatedness, and population structure within the data. We have previously used this method in Angus cattle using approximately 45,000 SNPs. In…

Nov. 2, 2017

Chung-Ho Lin

Lin is the lead scientist for the bioremediation, natural products and bioanalytical programs at the Center for Agroforestry at University of Missouri. His primary research involves the use of plants, microbes and engineered enzymes for bioremediation, ecological restoration, and development of bioeconomy. His bioremediation research focuses on bioremediation of organic pollutants and human pathogens. Since the COVID19 pandemic in 2020, Dr. Lin has successfully redirected the analytical resources and led his research team joining the task force ‘Coronavirus Sewershed Surveillance Project’ sponsored by the state and federal agencies to provide an early warning and capture the emergence…

Aug. 13, 2017

Peter Sutovsky

Peter Sutovsky is a Professor of Animal Science in the College of Agriculture, Food and Natural Resources, University of Missouri, also appointed as Professor of Obstetrics, Gynecology and Women’s Health at the School of Medicine, University of Missouri Health System. Since the early 90’s, Sutovsky has studied mammalian gametogenesis, fertilization, and pre-implantation embryonic development with special emphasis on the gamete and zygotic ubiquitin-proteasome system (UPS), publishing his work in Nature, Nature Communications, Nature Medicine, PNAS and other prestigious journals. He was the first to describe the role of UPS in the regulation of mitochondrial inheritance and introduced a novel…