Thomas Spencer

A light-skinned man with grey hair smiles. He is wearing a blue button-up shirt with a gold tie, and is against a grey background.

Ph.D.

Vice Chancellor for Research and Economic Development

University of Missouri Division of Research, Innovation and Impact

Curators' Distinguished Professor

Division of Animal Sciences

Research at a glance

Area(s) of Expertise

Research Summary

Tom Spencer is a reproductive and developmental biologist recognized for his work on the development and function of the uterus and placenta.

Spencer’s laboratory seeks to define critical physiological and genetic pathways that regulate uterine development, function, and regeneration in order to improve reproduction and health of women and animals. His earlier work established that the glands of the uterus are essential for embryo survival and growth using the ovine uterine gland knockout model. Subsequent research revealed fundamental aspects of postnatal uterine development and uterine receptivity as well as illuminated the evolutionary biology and functional role of endogenous retroviruses in placental development. Current research foci in his lab include: cellular and molecular mechanisms governing development of the uterus; maternal and paternal regulation of pregnancy establishment in cattle; placental development in domestic animals; development of animal models to study uterine function; and biological roles of uterine glands and their products in uterine receptivity, stromal cell decidualization, and placental development.

Educational background

  • Ph.D., Texas A&M University, 1995
  • PostDoc, Baylor College of Medicine, 1997