Reproductive Physiology and Molecular Biology, Genetic Engineering
Associate-Leader of Reproductive Biology Cluster
Food for the 21st Century
Director of the National Swine Resource and Research Center
- December 8, 2015 Scientists describe pigs that are resistant to porcine reproductive and respiratory syndrome virus.
- March 15, 2013 Missouri Agriculture magazine article featuring the National Swine Resource and Research Center
- May 5, 2010 Infection, Not Inflammation – An experimental animal model provides clues to better therapies for cystic fibrosis patients
- April 28, 2010 Scientists use pigs to try to beat cystic fibrosis
- Sept. 26, 2008 Pigs Bred with Cystic Fibrosis Provide Model to Mimic Human Disease
- March 6, 2008 Mizzou, Iowa Researchers Take First Step to Create Cystic Fibrosis Model using Pigs
Supplemental Material for Publications
- Whitworth KM, Mao J, Lee K, Spollen WG, Samuel MS, Walters EM, Spate LS, Prather RS Transcriptome analysis of pig in vivo, in vitro fertilized and nuclear transfer blastocyst stage embryos treated with histone deacetylase inhibitors post-fusion and activation reveals changes in the lysosomal pathway, Supplemental Material File 2 Excel; File 3 Excel; File 4 Excel; File 5 Excel; File 1 Excel; Table Word; Cellular Reprogramming 17:243-258.
- Zhao et al. Methylated DNA immunoprecipitation (MeDIP) by using low amounts of genomic DNA Supplemental Material. Cellular Reprogramming 16:175-184.
- Spate et al. Replacement of bovine serum albumin with N-methyl-D-aspartic acid and homocysteine improves development, but not live births.. Supplemental Material Molecular Reproduction and Development (79:310)
- Redel et al. Glycolysis in preimplantation development is partially controlled by the Warburg Effect. Table S1 and S2. Molecular Reproduction and Development (79:262-271)
- Whyte et al. Gene Targeting with Zinc Finger Nucleases to Produce Cloned eGFP Knockout Pigs. Supplemental Material (167KB pdf file) 2011 Molecular Reproduction and Development 78:2.
- Whitworth et al Scriptaid Corrects Gene Expression of a Few Aberrantly Reprogrammed Transcripts in Nuclear Transfer Pig Blastocyst Stage Embryos.Supplemental Material (54.5MB ZIP file) 2011 Cellular Reprogramming 13:191-204.
- Isom et al Transcriptional profiling of day 12 porcine embryonic disc and trophectoderm samples 1 using ultra deep sequencing technologies.Supplemental Material (21.3MB XLSX file) 2010 Molecular Reproduction and Development 77:812
- Whitworth et al Activation method does not alter abnormal placental gene expression and development in cloned pigs.Supplemental Material (3.79MB Zip file). 2010 Molecular Reproduction and Development 77:1016-1030.
- Bauer et al Transcriptional Profiling by Deep Sequencing Identifies Differences in mRNA Transcript Abundance in In Vivo Derived Vs. In Vitro Cultured Porcine Blastocyst Stage Embryos. Supplemental Material. 2010 Biology of Reproduction 83:791
- Bonk et al Aberrant DNA Methylation in Porcine in vitro-, parthenogenetic-, and somatic cell nuclear transfer-produced blastocysts.Supplemental Material. 2008 Molecular Reproduction and Development 75:250
- Bonk et al Correlation of developmental differences of nuclear transfer embryo cells to the methylation profiles of nuclear transfer donor cells in swine.Supplemental Material. 2007 Epigenetics 2:3, 179
- McHughes et al Identification and quantification of differentially represented transcripts in preimplantation bovine embryos.Supplemental Material – Bovine Spreadsheet (xls). 2009 Molecular Reproduction and Development 76:48
- Hao et al Porcine skin-derived stem cells can serve as donor cells for nuclear transfer.
Supplemental Material. 2009 Cloning and Stem Cells 11:10