Education

• Ph.D. University of Missouri, Columbia, Missouri 1981

Research

• Cell adhesion, extracellular matrix and cell signaling in the vascular wall
• Mechanotransduction and mechanodetection in vascular cells
• Regulation of vascular and cardiac responses to tissue injury by extracellular matrix derived signals
• Mechanisms of vascular remodeling
• Mechanisms responsible for the myogenic properties of vascular smooth muscle
• Applications of Atomic Force Microscopy, fluorescence microscopy and 3D-image analysis for studies of microvascular cell biology and the cyto-architecture and function of the microvessel wall
• Mechanisms of blood flow autoregulation