Disease ⋅ Page 1

ID’ing Mutant Proteins

Studies provide new insights into human metabolic disease

Mizzou research can help with patient diagnosis and development of therapeutic options for hypoglycemia, muscle disease and hormonal abnormalities.

A Nutty Pest

Black walnut curculio leads to crop loss

The black walnut curculio is a small insect that can have a big impact on black walnut crops. Trees infested with black walnut curculio can lose anywhere from a third to half of their nuts, says University of Missouri Extension state fruit specialist Michele Warmund. “Black walnut curculio overwinters in leaf litter or upper part of the soil,” Warmund says.…

Copper and Menkes

Biochemistry team discovers trigger to an often fatal disease

A team of Biochemistry researchers at the University of Missouri has published the first scientific evidence that the gene ATP7A is essential for the dietary absorption of the critical nutrient copper. This research explains why children with Menkes disease, who are born lacking this gene, develop a severe copper deficiency.

Pigs, with a similar respiratory makeup to humans, are the new research models in fighting cystic fibrosis

A New Model

Cystic fibrosis, an inherited chronic disease that affects the lungs and digestive system of about 30,000 children and adults in the U.S., has been a difficult disease to study as there are no effective animal models that mimic the human condition. That changed recently because University of Missouri and University of Iowa researchers can now produce pigs born with CF that have the exact symptoms of a newborn human with the disease.