Animal Reproductive Biology Group

Venkataseshu Ganjam

Professor
Veterinary Biomedical Sciences

Phone: 573-882-7830
E-mail: GanjamV@missouri.edu
Address: W118 Veterinary Medical Building

Education

D.V.M., India
Ph.D., Oklahoma State University, Stillwater

Research Focus

Sperm maturation
Testicular steroidogenesis

Research Description

Ganjam's primary goal is to elucidate the precise mechanisms involved in mammalian sperm maturation. Sperm acquire or develop the capacity for fertilization only during their transit through the epididymis, and knowledge of the sperm maturational process should enable its manipulation.

Ganjam's goals include clarifying the factors regulating epididymal 5a-reductase activity, understanding distribution and kinetics of epididymal androgen receptors, and establishing the interaction of androgen receptors and the epididymal 5a-reductase gene expression.

Currently, Ganjam is also investigating the putative role of 11b-hydroxysteroid dehydrogenase (11-HSD) in both testicular steroidogenesis and in epididymal physiology.

Recent Publications

Buff PR, Morrison CD, Ganjam VK, Keisler DH.
Effects of short-term feed deprivation and melatonin implants on circadian patterns of leptin in the horse. J Anim Sci. 2005 May;83(5):1023-32. PMID: 15827247
Johnson PJ, Slight SH, Ganjam VK, Kreeger JM.
Glucocorticoids and laminitis in the horse. Vet Clin North Am Equine Pract. 2002 Aug;18(2):219-36. Review. PMID: 15635906
Bowles DK, Maddali KK, Ganjam VK, Rubin LJ, Tharp DL, Turk JR, Heaps CL.
Endogenous testosterone increases L-type Ca2+ channel expression in porcine coronary smooth muscle. Am J Physiol Heart Circ Physiol. 2004 Nov;287(5):H2091-8. Epub 2004 Jul 8. PMID: 15242831
Philips BJ, Ansell PJ, Newton LG, Harada N, Honda S, Ganjam VK, Rottinghaus GE, Welshons WV, Lubahn DB.
Estrogen receptor-independent catechol estrogen binding activity: protein binding studies in wild-type, Estrogen receptor-alpha KO, and aromatase KO mice tissues. Biochemistry. 2004 Jun 1;43(21):6698-708. PMID: 15157104
Johnson PJ, Messer NT, Ganjam VK.
Cushing's syndromes, insulin resistance and endocrinopathic laminitis. Equine Vet J. 2004 Apr;36(3):194-8. No abstract available. PMID: 15147123
Johnson PJ, Ganjam VK, Slight SH, Kreeger JM, Messer NT.
Tissue-specific dysregulation of cortisol metabolism in equine laminitis. Equine Vet J. 2004 Jan;36(1):41-5. PMID: 14756370
Miller MA, Kottler SJ, Ramos-Vara JA, Johnson PJ, Ganjam VK, Evans TJ.
3-methylindole induces transient olfactory mucosal injury in ponies. Vet Pathol. 2003 Jul;40(4):363-70. PMID: 12824507
Johnson PJ, Messer NT 4th, Ganjam VK, Thompson DL Jr, Refsal KR, Loch WE, Ellersieck MR.
Effects of propylthiouracil and bromocryptine on serum concentrations of thyrotrophin and thyroid hormones in normal female horses. Equine Vet J. 2003 May;35(3):296-301. PMID: 12755434
Laughlin MH, Welshons WV, Sturek M, Rush JW, Turk JR, Taylor JA, Judy BM, Henderson KK, Ganjam VK.
Gender, exercise training, and eNOS expression in porcine skeletal muscle arteries. J Appl Physiol. 2003 Jul;95(1):250-64. Epub 2003 Mar 7. PMID: 12626483
Schwartz AJ, Wilson DA, Keegan KG, Ganjam VK, Sun Y, Weber KT, Zhang J.
Factors regulating collagen synthesis and degradation during second-intention healing of wounds in the thoracic region and the distal aspect of the forelimb of horses. Am J Vet Res. 2002 Nov;63(11):1564-70. PMID: 12428668
A complete list of publications for VK Ganjam in PubMed